Mucopolysaccharides of whole human spleens in generalized amyloidosis.
نویسندگان
چکیده
منابع مشابه
Mucopolysaccharides of whole human spleens in generalized amyloidosis.
Amyloidosis is a morphological concept (2) the diagnosis of which has been based on histological critera (3). "Primary" and "secondary" amyloidosis and the forms of amyloidosis seen in conjunction with familial Mediterranean fever (FMF) and myeloma are all grouped under one name because of morphological similarities, although it is not certain that they represent a single disease. Electron micr...
متن کاملMucopolysaccharides in human epidermis.
In a previous publication on the Gram staining material of human epidermis we advanced the theory that keratohyalin contained a highly resistant mucopolysaccharide. In the course of normal keratinization this material was decomposed, while in parakeratotic and many other types of pathologic scales it was retained in the horny layer (1). The evidence presented was indirect: we found that the ext...
متن کاملSphingomyelinase in normal human spleens and in spleens from subjects with Niemann-Pick disease.
This paper describes the purification and some of the properties of an enzyme from human spleen that catalyzes the hydrolysis of sphingomyelin with the formation of ceramide and phosphoryl choline. The enzyme, which is located in the subcellular particulate fraction that sediments between 700 and 8500 g, is readily made soluble and has been partially purified. Its pH optimum is between 4.5 and ...
متن کاملThe Sulfated Mucopolysaccharides Human Umbilical Cord*
Umbilical cord was shown to contain chondroitin sulfate B and a small amount of glucosamine-containing sulfated mucopolysaccharide, in addition to hyaluronic acid and chondroitin sulfate C. All of the hyaluronic acid and part of the chondroitin sulfate C could be extracted directly with dilute sodium chloride; the rest of the chondroitin sulfate C and the chondroitin sulfate B were released onl...
متن کاملThe occurrence of acid mucopolysaccharides in human leukocytes and urine.
Acid mucopolysaccharides have been found in urine (1) but have not been consistently demonstrated in the blood of normal subjects. Bassiouni (2) recently isolated a substance from leukocytes which he noted to be similar to chondroitin sulfate. In our laboratory leukocytes have been found to contain appreciable quantities of a substance resembling chondroitin sulfate. A direct relationship betwe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1966
ISSN: 0021-9738
DOI: 10.1172/jci105412